Centro di Saggio Europa - European Experimental Laboratory
Non-Clinical Research
The services of EEL include in vivo pharmacokinetic studies, toxicity and carcinogeniticy bioassays in laboratory animals (rat, mouse) following the OECD Guidelines for the Testing of Chemicals.
Protocols, data and reports are produced in accordance with defined international regulatory standards.
The studies are performed by fully trained researcher under supervision of experienced Study Director and Veterinary Surgeon.
Studies on repeated toxicity up to 6 month
- OECD Guideline 407: Repeated Dose 28-Day Oral Toxicity Study in Rodents
- OECD Guideline 408: Repeated Dose 90-Day Oral Toxicity Study in Rodents
- OECD Guideline 410: Repeated Dose Dermal Toxicity: 21/28-day Study
- OECD Guideline 411: Subchronic Dermal Toxicity: 90-day Study
Studies on chronic toxicity/carcinogenicity
- OECD Guideline 451: Carcinogenicity Studies
- OECD Guideline 452: Chronic Toxicity Study
- OECD Guideline 453: Combined Chronic Toxicity/Carcinogenicity Studies
Studies on metabolism/pharmacokinetics (in vivo phase)
- OECD Guideline 417: Toxicokinetics
