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In order to download Ramazzini study data in pdf or xml format, users are required to complete a simple registration. A unique password will be generated and sent to the e-mail address indicated in the registration form. Per scaricare i dati degli studi sperimentali Ramazzini in formato pdf o xml, gli utenti sono invitati a registrarsi. Una password personalizzata verrà generata e spedita all'indirizzo e-mail indicato nel modulo di registrazione. Register
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 November 15, 2008
EHP commentary argues the limits of 2-year bioassay exposure regimens: Ramazzini lifespan studies aspartame and toluene cited.
In a recent commentary entitled "The limits of 2-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens"Environ Health Perspect 116:11, 2008, authors James Huff, Devra Davis and Michael Jacobson argue that the sensitivity of chemical carcinogenesis bioassays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Citing lifespan studies conducted by the European Ramazzini Foundation on aspartame and toluene the authors conclude that observing rodents until their natural deaths (i.e the Ramazzini lifespan model) increases the sensitivity of bioassays, avoids false-negative results, and strengthens the value and validity of results for regulatory agencies.
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