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November 15, 2008 In a recent commentary entitled "The limits of 2-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens"Environ Health Perspect 116:11, 2008, authors James Huff, Devra Davis and Michael Jacobson argue that the sensitivity of chemical carcinogenesis bioassays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Citing lifespan studies conducted by the European Ramazzini Foundation on aspartame and toluene the authors conclude that observing rodents until their natural deaths (i.e the Ramazzini lifespan model) increases the sensitivity of bioassays, avoids false-negative results, and strengthens the value and validity of results for regulatory agencies. October 23, 2008 Da 26 anni il Collegium Ramazzini, un’accademia di esperti internazionali di scienze ambientali e medicina del lavoro, mette in collegamento il mondo delle scoperte scientifiche con gli enti sociali e le istituzioni pubbliche preposte all’utilizzo di queste scoperte per la conservazione della vita. Fondato nel 1982 dai Professori Irving J. Selikoff (USA), Cesare Maltoni (Italia) e da altri autorevoli scienziati, il Collegium terrà la sua riunione annuale a Carpi sabato 25 e domenica 26 ottobre 2008. Quest’anno il Collegium prenderà in esame alcune problematiche del futuro con una conferenza scientifica dal titolo “Nuovi agenti chimici, nanotecnologia e tutela della salute: le sfide da affrontare nel 21° secolo.” August 10, 2008 In September 2008 the ERF will be a part of the Italian delegation travelling to Beijing for the second meeting between the Italian League for the Fight Against Tumors (LILT) and the Chinese Association for the Control of Tumors (CACA). The event, held in conjunction with the 5th Chinese Conference on Oncology, will feature discussions on the environmental causes of cancer and the potential synergies between Western and traditional Chinese medicine in the fight against cancer. During the conference, ERF scientific director Dr. Morando Soffritti will speak on "Primary Prevention in Cancer Control" [Vedi testo completo per l'italiano]. March 14, 2008 La legge n. 266 del 23 dicembre 2005 prevede il meccanismo del 5 per mille: le persone fisiche possono destinare una parte delle imposte sui redditi a favore di Onlus autorizzate dall'Agenzia delle Entrate. Sia l'Istituto Nazionale Ramazzini che la Fondazione Europea Ramazzini possono ricevere questo contributo. Con un unico codice, è possibile sostenere tutti e due. |
 November 15, 2008
EHP commentary argues the limits of 2-year bioassay exposure regimens: Ramazzini lifespan studies aspartame and toluene cited.
In a recent commentary entitled "The limits of 2-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens"Environ Health Perspect 116:11, 2008, authors James Huff, Devra Davis and Michael Jacobson argue that the sensitivity of chemical carcinogenesis bioassays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Citing lifespan studies conducted by the European Ramazzini Foundation on aspartame and toluene the authors conclude that observing rodents until their natural deaths (i.e the Ramazzini lifespan model) increases the sensitivity of bioassays, avoids false-negative results, and strengthens the value and validity of results for regulatory agencies.
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