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11 - 20 of 97 Results - First experimental demonstration of the multipotential carcinogenic effects of aspartame administered in the feed to Sprague-Dawley rats View Pdf
 Soffritti M, Belpoggi F, Degli Esposti D, Lambertini L, Tibaldi E, Rigano A. 2006.
Environ Health Perspect 114:379-385, 2006. - Cancer Prevention: the lesson from the lab View Pdf
Soffritti M, Belpoggi F, Degli Esposti D. 2006.
In Biasco G., Tanneberger S.: Cancer Medicine at the Dawn of the 21st. Century: the view from Bologna 49-64. Bonomia University 2006. - Rischi Ambientali e Cancro
Soffritti M, Belpoggi F, Knowles K. 2006.
Ecologist Italiano, Libreria Editrice Fiorentina, 4:208-211, 2006. - Acesulfame Potassium: Soffritti responds View Pdf
Soffritti M. 2006.
Environ Health Perspect 114 A516-A519, 2006. - Aspartame induces lymphomas and leukaemias in rats View Pdf
Soffritti M, Belpoggi F, Degli Esposti D, Lambertini L. 2005.
Eur J Oncol 10:107-116, 2005. - Inquinamento atmosferico delle aree urbane e rischio di cancro View Pdf
Belpoggi F, Padovani M, Soffritti M. 2005.
Eur J Oncol 10:31-35, 2005. - Genetic testing at work: ethical and legal implications
Eds: Van Damme K, Sorsa M, Soffritti M, Minardi F, Brazier JV. 2005.
Eur J Oncol Library 4, 2005. - First experimental evidence of peritoneal and pleural mesotheliomas induced by fluoro-edenite fibres present in Etnean volcanic material from Biancavilla (Sicily, Italy) View Pdf
Soffritti M, Minardi F, Bua L, Degli Esposti D, Belpoggi F. 2004.
Eur J Oncol 9:169-175, 2004. - Implications of the Precautionary Principle for research and policy making View Pdf Order
Grandjean P, Bailar JC, Gee D, Needleman HL, Ozonoff DM, Richter E, Soffritti M, Soskolne CL. 2004.
Eur J Oncol 9:9-12, 2004. - Life-time carcinogenicity bioassays of toluene given by stomach tube to Sprague-Dawley rats View Pdf
Soffritti M, Belpoggi F, Padovani M, Lauriola M, Degli Esposti D, Minardi F. 2004.
Eur J Oncol 9:91-102, 2004.
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November 15, 2008
EHP commentary argues the limits of 2-year bioassay exposure regimens: Ramazzini lifespan studies aspartame and toluene cited.
In a recent commentary entitled "The limits of 2-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens" Environ Health Perspect 116:11, 2008, authors James Huff, Devra Davis and Michael Jacobson argue that the sensitivity of chemical carcinogenesis bioassays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Citing lifespan studies conducted by the European Ramazzini Foundation on aspartame and toluene the authors conclude that observing rodents until their natural deaths (i.e the Ramazzini lifespan model) increases the sensitivity of bioassays, avoids false-negative results, and strengthens the value and validity of results for regulatory agencies.
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