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  1. Results of a long-term carcinogenicity bioassay on vinyl acetate monomer in Wistar rats   View Pdf d

    Belpoggi F, Soffritti M, Minardi F, Ciliberti A, Padovani M, Cattin E, Maltoni C. 2002.
    Eur J Oncol 7:279-293, 2002.

  2. I mesoteliomi da amianto usato nelle Ferrovie Italiane: resoconto di 199 casi   View Pdf d

    Maltoni C, Lambertini L, Cevolani D, Minardi F, Soffritti M. 2002.
    Eur J Oncol 7:51-55, 2002.

  3. L'Hospice oncologico

    Maltoni C, Di Bisceglie M, Belpoggi F, Soffritti M. 2002.
    In De Luca A, Vignotto F.: Medicina Palliativa e Cure Palliative. Scienza Medica 11:440-466, 2002.

  4. Results of long-term experimental studies on the carcinogenicity of Ethylene-Bis-Dithiocarbamate (Mancozeb) in rats   View Pdf d   Order d

    Belpoggi F, Soffritti M, Bua L, Guarino M, Lambertini L, Cevolani D, Maltoni C. 2002.
    Ann NY Acad Sci 982:123-136, 2002.

  5. Results of long-term experimental studies on the carcinogenicity of Formaldehyde and Acetaldehyde in rats   View Pdf d   Order d

    Soffritti M, Belpoggi F, Lambertini L, Lauriola M, Padovani M, Maltoni C. 2002.
    Ann NY Acad Sci 982:87-105, 2002.

  6. Ramazzini Foundation Cancer Program: history and major projects, life-span carcinogenicity bioassay design, chemicals studied and results   View Pdf d   Order d

    Soffritti M, Belpoggi F, Minardi F, Maltoni C. 2002.
    Ann NY Acad Sci 982:26-45, 2002.

  7. Results of long-term carcinogenicity bioassay on vinyl acetate monomer in Sprague-Dawley rats   View Pdf d   Order d

    Minardi F, Belpoggi F, Soffritti M, Ciliberti A, Lauriola M, Cattin E, Maltoni C. 2002.
    Ann NY Acad Sci 982:106-122, 2002.

  8. Progetto di ricerche sperimentali sugli effetti antitumorali del leuprolide: il piano ed i primi risultati   View Pdf d

    Belpoggi F, Minardi F, Soffritti M, Bua L, Maltoni C. 2001.
    Eur J Oncol 6:411-416, 2001.

  9. Studi sperimentali della Fondazione Ramazzini sugli effetti cancerogeni delle radiazioni (raggi gamma, campi elettromagnetici a bassissima frequenza e radiofrequenza): progetti e primi risultati   View Pdf d

    Soffritti M, Belpoggi F, Lambertini L, Lenzi A, Minardi F, Bua L, Cevolani D, Maltoni C. 2001.
    Eur J Oncol 6:291-296, 2001.

  10. Chemioprevenzione dei tumori mammari: contributi sperimentali

    Minardi F, Soffritti M, Bua L, Guarino M, Padovani M, Maltoni C. 2001.
    Eur J Oncol 6: 3: 277-285, 2001.

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November 15, 2008
EHP commentary argues the limits of 2-year bioassay exposure regimens: Ramazzini lifespan studies aspartame and toluene cited.
In a recent commentary entitled "The limits of 2-Year Bioassay Exposure Regimens for Identifying Chemical Carcinogens"Environ Health Perspect 116:11, 2008, authors James Huff, Devra Davis and Michael Jacobson argue that the sensitivity of chemical carcinogenesis bioassays would be enhanced by exposing rodents beginning in utero and continuing for 30 months (130 weeks) or until their natural deaths at up to about 3 years. Citing lifespan studies conducted by the European Ramazzini Foundation on aspartame and toluene the authors conclude that observing rodents until their natural deaths (i.e the Ramazzini lifespan model) increases the sensitivity of bioassays, avoids false-negative results, and strengthens the value and validity of results for regulatory agencies.
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